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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRCH3
All Species:
8.79
Human Site:
S649
Identified Species:
21.48
UniProt:
Q96II8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96II8
NP_116162.1
777
86083
S649
D
S
I
T
G
Q
N
S
R
Q
R
E
E
E
L
Chimpanzee
Pan troglodytes
XP_001167088
777
86063
S649
D
S
I
T
G
Q
N
S
R
Q
R
E
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001118364
784
87008
S656
D
S
I
T
R
Q
N
S
R
Q
R
E
E
E
L
Dog
Lupus familis
XP_549199
765
84379
K661
N
N
L
E
S
R
L
K
V
I
L
P
D
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVU0
778
86321
E646
D
A
I
T
R
Q
R
E
E
E
L
K
L
I
D
Rat
Rattus norvegicus
NP_001100558
526
58586
D430
R
D
F
Q
K
T
E
D
M
K
R
Y
S
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516723
729
81318
E618
N
Q
L
R
K
N
I
E
F
R
L
K
V
S
L
Chicken
Gallus gallus
Q5ZLN0
603
67457
R507
V
I
N
L
S
F
N
R
F
K
V
F
P
S
V
Frog
Xenopus laevis
NP_001090023
601
66754
R505
S
R
L
P
V
T
L
R
E
P
I
G
E
S
L
Zebra Danio
Brachydanio rerio
Q7SXW3
601
67297
R505
S
V
I
L
S
F
N
R
F
K
S
F
P
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
81.6
44.2
N.A.
87.7
60.3
N.A.
74.7
21.7
39.7
21.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
84.3
60.4
N.A.
92
63.5
N.A.
80.3
38.4
51.9
38
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
26.6
6.6
N.A.
6.6
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
46.6
13.3
N.A.
33.3
20
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
10
0
0
0
0
0
10
0
0
0
0
10
10
10
% D
% Glu:
0
0
0
10
0
0
10
20
20
10
0
30
40
40
0
% E
% Phe:
0
0
10
0
0
20
0
0
30
0
0
20
0
0
0
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
50
0
0
0
10
0
0
10
10
0
0
10
10
% I
% Lys:
0
0
0
0
20
0
0
10
0
30
0
20
0
0
0
% K
% Leu:
0
0
30
20
0
0
20
0
0
0
30
0
10
0
50
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
20
10
10
0
0
10
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
10
0
10
20
0
0
% P
% Gln:
0
10
0
10
0
40
0
0
0
30
0
0
0
0
10
% Q
% Arg:
10
10
0
10
20
10
10
30
30
10
40
0
0
0
0
% R
% Ser:
20
30
0
0
30
0
0
30
0
0
10
0
10
30
0
% S
% Thr:
0
0
0
40
0
20
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
10
0
0
0
10
0
10
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _